Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

🔗 Learn more or get in touch:
🌐 Website: https://www.deryou-tw.com/
📧 Email: shela.a9119@msa.hinet.net
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Thailand OEM insole and pillow supplier

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.High-performance insole OEM Vietnam

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Indonesia anti-bacterial pillow ODM design

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Orthopedic pillow OEM development factory Taiwan

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Thailand neck support pillow OEM

The Earth Biogenome Project is aiming to sequence the genomes of all 1.8 million known complex life species on Earth within ten years. The Earth Biogenome Project aims to sequence the genomes of all complex life on Earth to revolutionize biological research and conservation. The Earth Biogenome Project is ramping up. It’s a global consortium that aims to sequence the genomes of all complex life on earth (some 1.8 million described species) in ten years. The project’s origins, aims, and progress are detailed in two multi-authored papers published on January 18, 2022. Once complete, it will forever change the way biological research is done. Specifically, researchers will no longer be limited to a few “model species” and will be able to mine the DNA sequence database of any organism that shows interesting characteristics. This new information will help us understand how complex life evolved, how it functions, and how biodiversity can be protected. The project was first proposed in 2016, and I was privileged to speak at its launch in London in 2018. It is currently in the process of moving from its startup phase to full-scale production. The aim of phase one is to sequence one genome from every taxonomic family on earth, some 9,400 of them. By the end of 2022, one-third of these species should be done. Phase two will see the sequencing of a representative from all 180,000 genera, and phase three will mark the completion of all the species. DNA sequence. The importance of weird species The grand aim of the Earth Biogenome Project is to sequence the genomes of all 1.8 million described species of complex life on Earth. This includes all plants, animals, fungi, and single-celled organisms with true nuclei (that is, all “eukaryotes”). While model organisms like mice, rock cress, fruit flies, and nematodes have been tremendously important in our understanding of gene functions, it’s a huge advantage to be able to study other species that may work a bit differently. Many important biological principles came from studying obscure organisms. For instance, genes were famously discovered by Gregor Mendel in peas, and the rules that govern them were discovered in red bread mold. DNA was discovered first in salmon sperm, and our knowledge of some systems that keep it secure came from research on tardigrades. Chromosomes were first seen in mealworms and sex chromosomes in a beetle (sex chromosome action and evolution has also been explored in fish and platypus). And telomeres, which cap the ends of chromosomes, were discovered in pond scum. Answering biological questions and protecting biodiversity Comparing closely and distantly related species provides tremendous power to discover what genes do and how they are regulated. For instance, in another PNAS paper, coincidentally also published on January 18, my University of Canberra colleagues and I discovered Australian dragon lizards regulate sex by the chromosome neighborhood of a sex gene, rather than the DNA sequence itself. Scientists also use species comparisons to trace genes and regulatory systems back to their evolutionary origins, which can reveal astonishing conservation of gene function across nearly a billion years. For instance, the same genes are involved in retinal development in humans and in fruit fly photoreceptors. And the BRCA1 gene that is mutated in breast cancer is responsible for repairing DNA breaks in plants and animals. The genome of animals is also far more conserved than has been supposed. For instance, several colleagues and I recently demonstrated that animal chromosomes are 684 million years old. It will be exciting, too, to explore the “dark matter” of the genome, and reveal how DNA sequences that don’t encode proteins can still play a role in genome function and evolution. Another important aim of the Earth Biogenome Project is conservation genomics. This field uses DNA sequencing to identify threatened species, which includes about 28% of the world’s complex organisms – helping us monitor their genetic health and advise on management. No longer an impossible task Until recently, sequencing large genomes took years and many millions of dollars. But there have been tremendous technical advances that now make it possible to sequence and assemble large genomes for a few thousand dollars. The entire Earth Biogenome Project will cost less in today’s dollars than the human genome project, which was worth about US$3 billion in total. In the past, researchers would have to identify the order of the four bases chemically on millions of tiny DNA fragments, then paste the entire sequence together again. Today they can register different bases based on their physical properties, or by binding each of the four bases to a different dye. New sequencing methods can scan long molecules of DNA that are tethered in tiny tubes, or squeezed through tiny holes in a membrane. Chromosomes consist of long double-helical arrays of the four base pairs whose sequence specifies genes. DNA molecules are capped at the end by telomeres. Why sequence everything? But why not save time and money by sequencing just key representative species? Well, the whole point of the Earth Biogenome Project is to exploit the variation between species to make comparisons, and also to capture remarkable innovations in outliers. There is also the fear of missing out. For instance, if we sequence only 69,999 of the 70,000 species of nematode, we might miss the one that could divulge the secrets of how nematodes can cause diseases in animals and plants. There are currently 44 affiliated institutions in 22 countries working on the Earth Biogenome Project. There are also 49 affiliated projects, including enormous projects such as the California Conservation Genomics Project, the Bird 10,000 Genomes Project and UK’s Darwin Tree of Life Project, as well as many projects on particular groups such as bats and butterflies. Written by Jenny Graves, Distinguished Professor of Genetics and Vice Chancellor’s Fellow, La Trobe University. This article was first published in The Conversation.

Recent research shows that babies use their early helplessness to develop cognitive models, similar to AI pre-training, challenging older theories about infant brain immaturity and potentially inspiring advancements in AI technology. Modern brain data does not support the classic explanation for infant helplessness. A new study suggests that babies’ brains are not as immature as previously believed; instead, they utilize their period of postnatal ‘helplessness’ to develop foundational models similar to those that drive generative Artificial Intelligence. The study finds for the first time that the classic explanation for infant helplessness is not supported by modern brain data. The research was led by a Trinity College Dublin neuroscientist and published in the journal Trends in Cognitive Sciences. Compared to many animals, humans are helpless for a long time after birth. Many animals, such as horses and chickens, can walk on the day they are born. This protracted period of helplessness puts human infants at risk and places a huge burden on the parents, but surprisingly has survived evolutionary pressure. Insights from a Cross-Species Study “Since the 1960s scientists have thought that the helplessness exhibited by human babies is due to the constraints of birth. The belief was that with big heads human babies have to be born early, resulting in immature brains and a helpless period that extends up to one year of age. We wanted to find out why human babies were helpless for such a long period,” explains Professor Rhodri Cusack, Professor of Cognitive Neuroscience, and lead author of the paper. The research team comprised Prof. Cusack, who measures the development of the infant brain and mind using neuroimaging; Prof. Christine Charvet, Auburn University, USA, who compares brain development across species; and Dr. Marc’Aurelio Ranzato, a senior AI researcher at DeepMind. “Our study compared brain development across animal species. It drew from a long-standing project, Translating Time, that equates corresponding ages across species to establish that human brains are more mature than many other species at birth,” says Prof. Charvet. The researchers used brain imaging and found that many systems in the human infant’s brain are already functioning and processing the rich streams of information from the senses. This contradicts the long-held belief that many infant brain systems are too immature to function. The team then compared learning in humans with the latest machine learning models, where deep neural networks benefit from a ‘helpless’ period of pre-training. In the past, AI models were directly trained on tasks for which they were needed for example a self-driving car was trained to recognize what they see on a road. But now models are initially pre-trained to see patterns within vast quantities of data, without performing any task of importance. The resulting foundation model is subsequently used to learn specific tasks. It has been found this ultimately leads to quicker learning of new tasks and better performance. Implications for Future AI Development “We propose that human infants similarly use the ‘helpless’ period in infancy to pre-train, learning powerful foundation models, which go on to underpin cognition in later life with high performance and rapid generalization. This is very similar to the powerful machine learning models that have led to the big breakthroughs in generative AI in recent years, such as OpenAI’s ChatGPT or Google’s Gemini,” Prof. Cusack explained. The researchers say that future research on how babies learn could well inspire the next generation of AI models. “Although there have been big breakthroughs in AI, foundation models consume vast quantities of energy and require vastly more data than babies. Understanding how babies learn may inspire the next generation of AI models. The next steps in research would be to directly compare learning in brains and AI,” he concluded. Reference: “Helpless infants are learning a foundation model” by Rhodri Cusack, Marc’Aurelio Ranzato and Christine J. Charvet, 4 June 2024, Trends in Cognitive Sciences. DOI: 10.1016/j.tics.2024.05.001 This research was supported by the European Research Council.

Illustration of the cyanobacterial thylakoid membrane. Credit: Luning Liu et al. A new study conducted by the researchers at the University of Liverpool reveals how the ancient photosynthetic organisms – cyanobacteria – evolve their photosynthetic machinery and organize their photosynthetic membrane architecture for the efficient capture of solar light and energy transduction. Oxygenic photosynthesis, carried out by plants, algae, and cyanobacteria, produces energy and oxygen for life on Earth and is arguably the most important biological process. Cyanobacteria are among the earliest phototrophs that can perform oxygenic photosynthesis and make significant contributions to the Earth’s atmosphere and primary production. Light-dependent photosynthetic reactions are performed by a set of photosynthetic complexes and molecules accommodated in the specialized cell membranes, called thylakoid membranes. While some studies have reported the structures of photosynthetic complexes and how they perform photosynthesis, researchers still had little understanding about how native thylakoid membranes are built and further developed to become a functional entity in cyanobacterial cells. The research team, led by Professor Luning Liu from the University’s Institute of Systems, Molecular and Integrative Biology, developed a method to control the formation of thylakoid membranes during cell growth and used state-of-the-art proteomics and microscopic imaging to characterize the stepwise maturation process of thylakoid membranes. Their results are published in the journal Nature Communications. “We are really thrilled about the findings,” said Professor Liu. “Our research draws a picture about how phototrophs generate and then develop their photosynthetic membranes, and how different photosynthetic components are incorporated and located in the thylakoid membrane to perform efficient photosynthesis – a long-standing question in this field.” The first author of the study, Dr. Tuomas Huokko, said: “We find that the newly synthesized thylakoid membranes emerge between the peripheral cell membrane, termed the plasma membrane, and the pre-existing thylakoid layer. By detecting the protein compositions and photosynthetic activities during the thylakoid development process, we also find that photosynthetic proteins are well controlled in space and time to evolve and assemble into the thylakoid membranes.” The new research shows that the cyanobacterial thylakoid membrane is a truly dynamic biological system and can adapt rapidly to environmental changes during bacterial growth. In thylakoids, photosynthetic proteins can diffuse from one position to another and form functional “protein islands” to work together for high photosynthetic efficiency. “Since cyanobacteria perform plant-like photosynthesis, the knowledge gained from cyanobacteria thylakoid membranes can be extended to plant thylakoids,” added Professor Liu. “Understanding how the natural photosynthetic machinery is evolved and regulated in phototrophs is vital for tuning and enhancing photosynthetic performance. This offers solutions to sustainably improve crop plant photosynthesis and yields, in the context of climate change and growing population. Our research may also benefit the bioinspired design and generation of artificial photosynthetic devices for efficient electron transfer and bioenergy production.” Reference: “Probing the biogenesis pathway and dynamics of thylakoid membranes” by Tuomas Huokko, Tao Ni, Gregory F. Dykes, Deborah M. Simpson, Philip Brownridge, Fabian D. Conradi, Robert J. Beynon, Peter J. Nixon, Conrad W. Mullineaux, Peijun Zhang and Lu-Ning Liu, 9 June 2021, Nature Communications. DOI: 10.1038/s41467-021-23680-1 The research was carried out in collaboration with the University’s Centre for Proteome Research, Centre for Cell Imaging, and Biomedical Electron Microscopy Unit, as well as with researchers from University of Oxford, Queen Mary University of London, and Imperial College London. The research was funded by the BBSRC, Royal Society, Wellcome Trust, and Leverhulme Trust.

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